Warning: The only drawback is that the Multiresolution Modifier does not allow you to freely switch between subdivision types at a specific level. Switching from Catmull-Clark to Simple (or vice versa) affects all multires levels.
Tip: If you have a subdivision surface modifier on your mesh, we recommend applying it to your mesh or removing it from the modifier stack before adding the multiresolution modifier. Since the Multiresolution Modifier uses the same process to create subdivision levels, you don’t have to be both active at the same time.
After you have added a level, you will have some additional options. If you click “higher removes”, All Subdivision levels larger than the level you are currently in will be removed. So if you have five subdivision levels and you are at level 3, click “delete higher” to effectively eliminate levels 4 and 5.
Selecting the Optimal Draw check box does the same thing as the corresponding check box in the Surface Modifier subdivision: it prevents Blender from displaying divided edges in the 3D view.
Some 3D modelers who use Scultping like to place the model’s wireframe on the mesh (Object Properties > Display > Wire) while working, so they have an idea of what their topology looks like. Without the “Optimal Draw” option, the 3D view of your model can quickly become overloaded, so checking this box simplifies the display for you.
Now, when you try to enter edit mode on a Multires mesh, you will still only see the nodes available to you in the cage of the basic mesh. So how do you actually edit as the additional nodes created by the Multiresolution Modifier?